Dr Janna Luessing
Senior Researcher
Hosted by Noel Lowndes
SFI-IRC Pathway Programme

Research interests

  • Understanding the roles for Zinc finger proteins in DNA repair
  • Elucidating the functions of PIK kinases in cytokinesis
  • Characterise novel, naturally occurring ATR mutations

Research overview

Mutations caused by damage to our genetic material can result in genome instability. These mutations can either be silent and inconsequential or they can lead to cell death or uncontrolled cell growth that is a characteristic of cancer. Our research aims to gain further insights into how cells maintain their genetic stability. Specifically, the focus of my research is to elucidate novel functions for two Zinc finger proteins in DNA repair. These proteins have been previously implicated in intellectual disability and viral infection.

Selected Figures


DNA repair, ATR, Zinc-finger proteins, abscission

Lab Members

Áine Murphy (PhD)

Key Research Techniques

  • Cell culture
  • Microscopy
  • Protein Biochemistry and Proteomics
  • Genome editing and Genomics

Selected publications

Most Recent Publications

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